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Epclusa (sofosbuvir/velpatasvir)Blue Cross Blue Shield of Illinois

Chronic hepatitis C virus (HCV) infection

Preferred products

  • Epclusa (sofosbuvir/velpatasvir)
  • Harvoni (ledipasvir/sofosbuvir)
  • Ledipasvir/Sofosbuvir
  • Sofosbuvir/Velpatasvir
  • Mavyret (glecaprevir/pibrentasvir)
  • Zepatier (elbasvir/grazoprevir)

Initial criteria

  • Patient has an FDA labeled diagnosis for the requested agent
  • Requested agent is FDA labeled for treatment of the patient’s genotype
  • Patient’s age is within or supported for FDA labeling
  • HBV screening completed and monitored if positive
  • Patient does not have any FDA labeled contraindications
  • Prescriber is a specialist or has consulted with specialist OR patient qualifies for simplified treatment per AASLD guidelines and meets qualifying/exclusion criteria
  • If the client has preferred agent(s), patient meets one of the exception conditions to use non-preferred agent

Approval duration

Duration per FDA labeling