Vfend (voriconazole) — Blue Cross Blue Shield of Illinois
invasive aspergillosis
Preferred products
- fluconazole
 
Initial criteria
- Diagnosis of invasive aspergillosis OR
 - Prophylaxis of invasive aspergillosis or Candida AND patient is severely immunocompromised (e.g., HSCT, hematologic malignancy with prolonged neutropenia, high-risk solid organ transplant) OR
 - Diagnosis of esophageal candidiasis, candidemia, or other deep tissue Candida infection AND ONE of the following: (stage 4 advanced metastatic cancer with treatment consistent with best practices) OR inadequate response to fluconazole OR intolerance or hypersensitivity to fluconazole OR FDA labeled contraindication to fluconazole OR
 - Diagnosis of serious infection caused by Scedosporium or Fusarium species OR
 - Other FDA labeled indication or compendia supported indication AND
 - If patient has an FDA labeled indication, age within labeling or supported for indication AND
 - Patient does not have any FDA labeled contraindications to requested agent
 
Reauthorization criteria
- Patient has been previously approved for the requested agent through plan prior authorization review AND
 - EITHER: (diagnosis of invasive aspergillosis; serious infection caused by Scedosporium or Fusarium species; esophageal candidiasis; candidemia; or deep tissue Candida infection) OR (other diagnosis supported for continued use)
 
Approval duration
6 months (BCBSIL/BCBSMT); 3 months (BCBSNM esophageal candidiasis)/6 months others; 1 month (other plans esophageal candidiasis)/6 months others