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Vfend (voriconazole)Blue Cross Blue Shield of Illinois

other FDA labeled indication

Preferred products

  • fluconazole

Initial criteria

  • Diagnosis of invasive aspergillosis OR
  • Prophylaxis of invasive aspergillosis or Candida AND patient is severely immunocompromised (e.g., HSCT, hematologic malignancy with prolonged neutropenia, high-risk solid organ transplant) OR
  • Diagnosis of esophageal candidiasis, candidemia, or other deep tissue Candida infection AND ONE of the following: (stage 4 advanced metastatic cancer with treatment consistent with best practices) OR inadequate response to fluconazole OR intolerance or hypersensitivity to fluconazole OR FDA labeled contraindication to fluconazole OR
  • Diagnosis of serious infection caused by Scedosporium or Fusarium species OR
  • Other FDA labeled indication or compendia supported indication AND
  • If patient has an FDA labeled indication, age within labeling or supported for indication AND
  • Patient does not have any FDA labeled contraindications to requested agent

Reauthorization criteria

  • Patient has been previously approved for the requested agent through plan prior authorization review AND
  • EITHER: (diagnosis of invasive aspergillosis; serious infection caused by Scedosporium or Fusarium species; esophageal candidiasis; candidemia; or deep tissue Candida infection) OR (other diagnosis supported for continued use)

Approval duration

6 months (BCBSIL/BCBSMT); 3 months (BCBSNM esophageal candidiasis)/6 months others; 1 month (other plans esophageal candidiasis)/6 months others