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RezdiffraBlue Cross Blue Shield of Kansas

metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis (stage F2–F3) without cirrhosis

Initial criteria

  • Patient is age ≥ 18 years
  • Diagnosis of metabolic dysfunction-associated steatohepatitis (MASH) or nonalcoholic steatohepatitis (NASH) confirmed by liver biopsy or noninvasive methods showing fibrosis stage F2 or F3
  • No evidence of cirrhosis (fibrosis stage F4 or higher)
  • Prescriber attests that the patient will continue lifestyle modification (diet, exercise, alcohol avoidance, weight loss) alongside pharmacologic therapy

Reauthorization criteria

  • Patient has demonstrated stability or improvement in liver fibrosis or biochemical markers of steatohepatitis upon review
  • Prescriber attests therapy remains clinically appropriate and well-tolerated

Approval duration

12 months