Viekira PAK (ombitasvir/paritaprevir/ritonavir + dasabuvir) — Blue Cross Blue Shield of Kansas
chronic hepatitis C virus (HCV) infection (genotypes 1–6)
Preferred products
- Epclusa (sofosbuvir/velpatasvir)
- Harvoni (ledipasvir/sofosbuvir)
- Ledipasvir/Sofosbuvir
- Mavyret (glecaprevir/pibrentasvir)
- Vosevi (sofosbuvir/velpatasvir/voxilaprevir)
Initial criteria
- Patient has an FDA labeled diagnosis for the requested agent
- Requested agent is FDA labeled for the patient's genotype
- If patient has FDA labeled indication, ONE of: (A) patient’s age is within FDA labeling OR (B) there is support for use in patient’s age for the indication
- If FDA labeling requires hepatitis B screening, BOTH: (A) prescriber has screened for current/prior HBV infection AND (B) if positive, prescriber will monitor for HBV flare-up or reactivation during and after treatment
- Patient does NOT have any FDA labeled contraindications to requested agent
- ONE of: (A) prescriber is specialist (gastroenterologist, hepatologist, infectious disease) or has consulted one OR (B) ALL: patient is treatment naïve AND no cirrhosis or compensated cirrhosis AND requested agent is supported in AASLD simplified treatment AND patient meets qualifications for simplified treatment
- If client has preferred agent(s) for patient’s factors (age, genotype, cirrhosis, treatment history), ONE of: (A) requested agent is preferred OR (B) patient recently treated with requested non-preferred OR (C) intolerance/hypersensitivity to ALL preferred OR (D) FDA labeled contraindication to ALL preferred OR (E) clinical information supports use of non-preferred over preferred agent
- Patient meets all requirements and will use requested agent in a treatment regimen per Table 11 FDA labeling
- Requested length of therapy does NOT exceed Table 11
Approval duration
up to duration of treatment per Table 11