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The Policy VaultThe Policy Vault

Viekira PAK (ombitasvir/paritaprevir/ritonavir + dasabuvir)Blue Cross Blue Shield of Kansas

chronic hepatitis C virus (HCV) infection (genotypes 1–6)

Preferred products

  • Epclusa (sofosbuvir/velpatasvir)
  • Harvoni (ledipasvir/sofosbuvir)
  • Ledipasvir/Sofosbuvir
  • Mavyret (glecaprevir/pibrentasvir)
  • Vosevi (sofosbuvir/velpatasvir/voxilaprevir)

Initial criteria

  • Patient has an FDA labeled diagnosis for the requested agent
  • Requested agent is FDA labeled for the patient's genotype
  • If patient has FDA labeled indication, ONE of: (A) patient’s age is within FDA labeling OR (B) there is support for use in patient’s age for the indication
  • If FDA labeling requires hepatitis B screening, BOTH: (A) prescriber has screened for current/prior HBV infection AND (B) if positive, prescriber will monitor for HBV flare-up or reactivation during and after treatment
  • Patient does NOT have any FDA labeled contraindications to requested agent
  • ONE of: (A) prescriber is specialist (gastroenterologist, hepatologist, infectious disease) or has consulted one OR (B) ALL: patient is treatment naïve AND no cirrhosis or compensated cirrhosis AND requested agent is supported in AASLD simplified treatment AND patient meets qualifications for simplified treatment
  • If client has preferred agent(s) for patient’s factors (age, genotype, cirrhosis, treatment history), ONE of: (A) requested agent is preferred OR (B) patient recently treated with requested non-preferred OR (C) intolerance/hypersensitivity to ALL preferred OR (D) FDA labeled contraindication to ALL preferred OR (E) clinical information supports use of non-preferred over preferred agent
  • Patient meets all requirements and will use requested agent in a treatment regimen per Table 11 FDA labeling
  • Requested length of therapy does NOT exceed Table 11

Approval duration

up to duration of treatment per Table 11