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alpelisib (pros)Blue Cross Blue Shield of Montana

PIK3CA-Related Overgrowth Spectrum (PROS) - Quantity Limit

Initial criteria

  • The requested quantity (dose) does NOT exceed the program quantity limit OR
  • The requested quantity (dose) exceeds the program quantity limit AND ONE of the following: A. BOTH of the following: 1. The requested quantity (dose) does NOT have a maximum FDA labeled dose for the requested indication AND 2. There is support for therapy with a higher dose for the requested indication OR B. BOTH of the following: 1. The requested quantity (dose) does NOT exceed the maximum FDA labeled dose for the requested indication AND 2. There is support for why the requested quantity (dose) cannot be achieved with a lower quantity of a higher strength that does NOT exceed the program quantity limit

Approval duration

6 months initial; 12 months renewal (BCBSIL 12 months)