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HympavziBlue Cross Blue Shield of Montana

Off-label uses for BCBS MT, NM, and OH members per plan exceptions

Initial criteria

  • BCBS MT Fully Insured or MT HIM members:
  • • Patient age < 18 years
  • • No FDA labeled contraindications
  • • Indication supported in TWO articles from major peer-reviewed journals (e.g., JAMA, NEJM, Lancet) as generally safe and effective (case studies not accepted)
  • • Age support in TWO peer-reviewed articles for same age bracket (infancy, childhood, adolescence) as generally safe and effective
  • BCBS NM Fully Insured or NM HIM members:
  • • No FDA labeled contraindications
  • • Indication is rare disease
  • • ONE of:
  • - Has another FDA labeled indication for requested agent and route OR
  • - Has another indication supported in compendia OR
  • - Submitted TWO peer-reviewed articles showing proposed use generally safe and effective
  • OH Fully Insured or HIM Shop (SG) members:
  • • Member resides in Ohio
  • • Plan is Fully Insured or HIM Shop (SG)
  • • No FDA labeled contraindications
  • • ONE of:
  • - Has another FDA labeled indication for requested agent and route OR
  • - Has another indication supported in compendia OR
  • - TWO peer-reviewed journal articles (JAMA, NEJM, Lancet) support proposed use as generally safe and effective (case studies not acceptable)

Approval duration

12 months (all except BCBSOK 36 months)