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Mekinist oral solutionBlue Cross Blue Shield of Oklahoma

stage four advanced metastatic cancer or associated condition

Preferred products

  • Mekinist oral tablets

Initial criteria

  • ONE of the following:
  • A. Patient weighs less than 26 kg OR
  • B. BOTH of the following:
  • 1. Diagnosis of stage four advanced, metastatic cancer and requested agent used to treat cancer or associated condition AND
  • 2. Use consistent with best practices supported by peer-reviewed evidence and FDA approval OR
  • C. Currently treated and stable on requested agent OR
  • D. Tried and had inadequate response to Mekinist oral tablets OR
  • E. Mekinist oral tablets discontinued due to lack of efficacy, diminished effect, or adverse event OR
  • F. Intolerance or hypersensitivity to Mekinist oral tablets not expected with requested agent OR
  • G. FDA labeled contraindication to Mekinist oral tablets not expected with requested agent OR
  • H. Mekinist oral tablets expected to be ineffective, cause adherence barrier, worsen comorbidity, decrease function, or cause harm OR
  • I. Mekinist oral tablets not in best interest of patient OR
  • J. Tried another drug in same class as Mekinist oral tablets discontinued due to efficacy or adverse event OR
  • K. Support for use over Mekinist oral tablets (e.g., swallowing difficulties)