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Motegrity (prucalopride)Blue Cross Blue Shield of Oklahoma

chronic idiopathic constipation (CIC)

Preferred products

  • Trulance (plecanatide)
  • Linzess (linaclotide)

Initial criteria

  • Patient has diagnosis of chronic idiopathic constipation (CIC) AND symptoms for ≥3 months
  • Requested agent is Amitiza (lubiprostone) or Motegrity (prucalopride)
  • AND ONE of the following: BOTH of the following: prescriber statement or documentation of stage four advanced metastatic cancer AND agent use consistent with best practices and FDA approval OR patient has tried and had inadequate response to ≥2 standard laxative therapy classes OR patient has intolerance or hypersensitivity to ≥2 standard laxative therapy classes OR patient has FDA labeled contraindication to ALL standard laxative therapy classes