Otezla/otezla xr 28 day t — Blue Cross Blue Shield of Oklahoma
Behcet’s disease (BD)
Initial criteria
- ONE of the following:
 - A. Continuation of therapy: prescriber states the patient has been treated with the requested agent (not from samples) within the past 90 days AND is at risk if therapy is changed OR
 - B. BOTH of the following: (disease-specific criteria below)
 - For Psoriatic Arthritis (PsA):
 - – Patient has diagnosis of active PsA AND ONE of the following:
 - 1. Has tried and had inadequate response to ONE conventional agent (cyclosporine, leflunomide, methotrexate, sulfasalazine) after at least 3 months OR
 - 2. Has intolerance or hypersensitivity to ONE conventional agent used for PsA OR
 - 3. Has FDA-labeled contraindication to ALL conventional agents for PsA OR
 - 4. Medication history indicates use of another biologic immunomodulator agent FDA labeled or supported in compendia for PsA.
 - For Plaque Psoriasis (PS):
 - – Patient has diagnosis of plaque psoriasis AND BOTH of the following:
 - 1. Either:
 - A. Adult with mild to severe plaque psoriasis OR
 - B. Pediatric patient age ≥ 6 years, with moderate to severe plaque psoriasis AND weight ≥ 20 kg.
 - 2. ONE of the following:
 - A. Has tried and had inadequate response to ONE conventional agent (acitretin, anthralin, calcipotriene, calcitriol, coal tar products, cyclosporine, methotrexate, pimecrolimus, PUVA, tacrolimus, tazarotene, topical corticosteroids) after at least 3 months OR
 - B. Has intolerance or hypersensitivity to ONE conventional agent for PS OR
 - C. Has FDA-labeled contraindication to ALL conventional agents for PS OR
 - D. Medication history indicates use of another biologic immunomodulator agent FDA labeled or supported in compendia for PS.
 - For Behcet’s disease (BD):
 - – Patient has diagnosis of BD AND ALL of the following:
 - 1. Active oral ulcers associated with BD AND
 - 2. ≥ 3 occurrences of oral ulcers in the last 12 months AND
 - 3. ONE of the following:
 - A. Has tried and had inadequate response to ONE conventional agent (topical oral corticosteroids [e.g., triamcinolone dental paste], colchicine) OR
 - B. Has intolerance or hypersensitivity to ONE conventional agent used for BD OR
 - C. Has FDA-labeled contraindication to ALL conventional agents for BD OR
 - D. Medication history indicates use of another biologic immunomodulator agent FDA labeled or supported in compendia for BD.