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AranespBlue Cross Blue Shield of Texas

Anemia in cancer patients with non-myeloid metastatic malignancies receiving myelosuppressive chemotherapy

Initial criteria

  • Prior to starting the requested agent, ferritin ≥ 100 ng/mL OR transferrin saturation ≥ 20%
  • Iron stores maintained before and during ESA therapy
  • Blood pressure adequately controlled before and during ESA therapy
  • ESA dose is the lowest to avoid RBC transfusion need
  • Prescriber is a nephrologist, oncologist, or has consulted with one
  • Patient has no FDA labeled contraindications

Approval duration

12 months (CKD, MDS, HIV anemia); 6 months (chemotherapy anemia, other diagnoses)