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FuroscixBlue Cross Blue Shield of Texas

off-label indication supported by published medical literature

Initial criteria

  • The request is for a BCBS NM Fully Insured or NM HIM member and ALL of the following:
  • A. The patient does NOT have any FDA labeled contraindications to the requested agent AND
  • B. The requested indication is a rare disease AND
  • C. ONE of the following:
  • 1. The patient has another FDA labeled indication for the requested agent and route of administration OR
  • 2. The patient has another indication that is supported in compendia for the requested agent and route of administration OR
  • For members residing in Ohio with Fully Insured or HIM Shop (SG) plan ALL of the following:
  • A. The member resides in Ohio AND
  • B. The plan is Fully Insured or HIM Shop (SG) AND
  • C. The patient does NOT have any FDA labeled contraindications to the requested agent AND
  • D. ONE of the following:
  • 1. The patient has another FDA labeled indication for the requested agent and route of administration OR
  • 2. The patient has another indication that is supported in compendia for the requested agent and route of administration OR
  • 3. The prescriber has submitted TWO articles from major peer-reviewed professional medical journals supporting the proposed use(s) as generally safe and effective (case studies not acceptable)
  • Non-oncology compendia allowed: DrugDex level 1, 2A or 2B, AHFS-DI supportive narrative
  • Oncology compendia allowed: NCCN 1 or 2A, AHFS-DI supportive narrative, DrugDex level 1, 2A, or 2B, or Clinical Pharmacology supportive narrative, LexiDrugs evidence level A, peer-reviewed medical literature

Approval duration

12 months