lotilaner ophthalmic solution 0.25% — Blue Cross Blue Shield of Texas

Initial criteria

• ONE of the following:
• A. The patient has a diagnosis of Demodex blepharitis AND ALL of the following:
• 1. The patient has ONE of the following signs of Demodex infestation: Collarettes (cylindrical dandruff at the eyelash base) OR Lid margin erythema or edema OR Conjunctival injection OR Eyelash misdirection/irregularity AND
• 2. The patient has ONE of the following symptoms of Demodex infestation: Blurred/fluctuating vision OR Discharge or crusting on lashes OR Dryness OR Foreign body sensation OR Itching OR Pain/burning OR Watering/tearing AND
• 3. The patient has ONE of the following (medical records required): currently being treated with the requested agent and stable OR tried tea tree oil eyelid scrubs for ≥ 6 weeks with inadequate response OR tea tree oil eyelid scrubs discontinued due to lack of efficacy/effectiveness, diminished effect, or an adverse event OR has intolerance or hypersensitivity to tea tree oil eyelid scrubs OR has FDA labeled contraindication to tea tree oil eyelid scrubs OR tea tree oil eyelid scrubs expected to be ineffective based on clinical characteristics OR tea tree oil eyelid scrubs not in the best interest of the patient based on medical necessity OR tried another prescription drug in same pharmacologic class or mechanism as tea tree oil eyelid scrubs and discontinued due to lack of efficacy/effectiveness, diminished effect, or an adverse event
• B. The patient has another FDA labeled indication for the requested agent and route of administration OR
• C. The patient has another indication supported in compendia for the requested agent and route of administration AND
• The prescriber is a specialist in the area of the patient’s diagnosis (e.g., ophthalmologist, optometrist), or has consulted with a specialist AND
• The patient does NOT have any FDA labeled contraindications to the requested agent

Approval duration

BCBSIL: 12 months; BCBSMT/NM: 3 months; All other plans: 2 months