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Mekinist oral solutionBlue Cross Blue Shield of Texas

stage four advanced, metastatic cancer

Initial criteria

  • ONE of the following:
  • A. Patient weighs less than 26 kg OR
  • B. BOTH of the following:
  • 1. Prescriber states or documents stage four advanced, metastatic cancer and requested agent used to treat it OR associated condition [chart notes required]
  • 2. Use consistent with best practices, supported by evidence-based literature, and FDA approved
  • C. Patient currently treated and stable on requested agent [chart notes required]
  • D. Patient tried and had inadequate response to Mekinist oral tablets [chart notes required]
  • E. Mekinist tablets discontinued due to lack of efficacy, effectiveness, diminished effect, or adverse event [chart notes required]
  • F. Patient has intolerance or hypersensitivity to Mekinist tablets not expected with requested agent [chart notes required]
  • G. Patient has FDA labeled contraindication to Mekinist tablets not expected with requested agent [chart notes required]
  • H. Mekinist tablets expected to be ineffective OR cause adherence barrier OR worsen comorbidities OR decrease functional ability OR cause harm [chart notes required]
  • I. Mekinist tablets not in best interest of patient based on medical necessity [chart notes required]
  • J. Patient tried another drug in same class as Mekinist tablets discontinued for lack of efficacy or adverse event [chart notes required]
  • K. Support for use of requested agent over Mekinist tablets (e.g., swallowing difficulties)

Approval duration

12 months