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requested agent (imatinib tablet alternatives)Blue Cross Blue Shield of Texas

stage four advanced, metastatic cancer

Initial criteria

  • ONE of the following:
  • A. Prescriber states or documents stage four advanced, metastatic cancer and requested agent used to treat it OR associated condition [chart notes required] AND the use is consistent with best practices, supported by evidence-based literature, and FDA approved
  • B. Patient currently treated and stable on requested agent [chart notes required]
  • C. Patient tried and had inadequate response to imatinib tablets [chart notes required]
  • D. Imatinib tablets discontinued due to lack of efficacy, effectiveness, diminished effect, or adverse event [chart notes required]
  • E. Patient has intolerance or hypersensitivity to imatinib tablets not expected with requested agent [chart notes required]
  • F. Patient has FDA labeled contraindication to imatinib tablets not expected with requested agent [chart notes required]
  • G. Imatinib tablets expected to be ineffective OR cause adherence barrier OR worsen comorbidities OR decrease functional ability OR cause adverse reaction or harm [chart notes required]
  • H. Imatinib tablets not in best interest of patient based on medical necessity [chart notes required]
  • I. Patient tried another drug in same class or mechanism as imatinib that was discontinued due to lack of efficacy, diminished effect, or adverse event [chart notes required]
  • J. Support for use of requested agent over imatinib (e.g., swallowing difficulties)

Approval duration

12 months