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AdempasCareFirst (Caremark)

Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Initial criteria

  • Medication must be prescribed by or in consultation with a pulmonologist or cardiologist.
  • For Pulmonary Arterial Hypertension (PAH):
  • Member has PAH defined as WHO Group 1 class of pulmonary hypertension.
  • PAH was confirmed by right heart catheterization with all of the following pretreatment results:
  • Mean pulmonary arterial pressure (mPAP) > 20 mmHg
  • Pulmonary capillary wedge pressure (PCWP) ≤ 15 mmHg
  • Pulmonary vascular resistance (PVR) > 2 Wood units.
  • For Chronic Thromboembolic Pulmonary Hypertension (CTEPH):
  • Member has CTEPH defined as WHO Group 4 class of pulmonary hypertension.
  • Member has either recurrent or persistent CTEPH after pulmonary endarterectomy (PEA) OR inoperable CTEPH with diagnosis confirmed by BOTH of the following:
  • Computed tomography (CT)/magnetic resonance imaging (MRI) angiography or pulmonary angiography.
  • Pretreatment right heart catheterization with all of the following results:
  • mPAP > 20 mmHg
  • PCWP ≤ 15 mmHg
  • PVR > 2 Wood units.

Reauthorization criteria

  • Member has an indication listed in the coverage criteria.
  • Member is currently receiving the requested medication through a paid pharmacy or medical benefit.
  • Member is experiencing benefit from therapy as evidenced by disease stability or disease improvement.

Approval duration

12 months