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The Policy VaultThe Policy Vault

Akeega (niraparib and abiraterone acetate)CareFirst (Caremark)

metastatic castration‑resistant prostate cancer (mCRPC) with deleterious or suspected deleterious BRCA‑mutated (BRCAm) disease

Initial criteria

  • member has a diagnosis of metastatic castration‑resistant prostate cancer
  • disease has deleterious or suspected deleterious BRCA mutation confirmed by laboratory report
  • member has had a bilateral orchiectomy OR will be using the requested medication in combination with a luteinizing hormone‑releasing hormone (LHRH) agonist (e.g., goserelin, leuprolide) or antagonist (e.g., degarelix, relugolix)
  • requested medication will be used in combination with prednisone

Reauthorization criteria

  • member is requesting reauthorization for an indication listed in the coverage criteria
  • no evidence of unacceptable toxicity
  • no evidence of disease progression while on the current regimen

Approval duration

12 months