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AranespCareFirst (Caremark)

Myelofibrosis-associated anemia

Initial criteria

  • Pretreatment hemoglobin < 10 g/dL
  • Pretreatment serum erythropoietin (EPO) level < 500 mU/mL
  • Member has been assessed for iron deficiency anemia and has adequate iron stores (TSAT ≥ 20% within the prior 3 months) or is receiving iron therapy
  • Member is not using other erythropoiesis-stimulating agents concomitantly

Reauthorization criteria

  • After at least 12 weeks of treatment, member has a rise in hemoglobin ≥ 1 g/dL
  • Current hemoglobin < 12 g/dL
  • Member continues to have myelofibrosis-associated anemia
  • Member has adequate iron stores (TSAT ≥ 20% within 3 months) or is receiving iron therapy
  • Member is not using other erythropoiesis-stimulating agents concomitantly

Approval duration

12 weeks