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Arcalyst (rilonacept)CareFirst (Caremark)

Deficiency of Interleukin-1 Receptor Antagonist (DIRA)

Preferred products

  • Kineret (anakinra)

Initial criteria

  • Member weighs ≥ 10 kg
  • Member has IL1RN gene variants
  • Arcalyst will be used for maintenance of remission following treatment with Kineret (anakinra)
  • Member has had a documented negative tuberculosis (TB) test within 12 months of initiating therapy or treatment completed for latent TB as applicable
  • Member will not use the requested medication concomitantly with any other biologic drug or targeted synthetic drug
  • Prescribed by or in consultation with a rheumatologist or immunologist

Reauthorization criteria

  • Member weighs ≥ 10 kg
  • Member achieves or maintains a positive clinical response as evidenced by low disease activity or improvement in signs and symptoms of the condition

Approval duration

12 months