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Bimzelx (bimekizumab-bkzx)CareFirst (Caremark)

active ankylosing spondylitis (AS)

Initial criteria

  • Member is an adult (age ≥ 18 years) with active ankylosing spondylitis or active non-radiographic axial spondyloarthritis.
  • Authorization of 12 months may be granted for members who have previously received a biologic or targeted synthetic drug (e.g., Rinvoq, Xeljanz) indicated for active AS or nr-axSpA.
  • Authorization of 12 months may be granted when either of the following is met:
  • • Member has had an inadequate response to at least two nonsteroidal anti-inflammatory drugs (NSAIDs).
  • • Member has an intolerance or contraindication to two or more NSAIDs.
  • Negative TB test documented if biologic naïve.
  • Member cannot use Bimzelx concomitantly with any other biologic drug or targeted synthetic drug for the same indication.

Reauthorization criteria

  • Adult member demonstrates positive clinical response with improvement in any of the following from baseline:
  • • Functional status
  • • Total spinal pain
  • • Inflammation (e.g., morning stiffness)
  • • Swollen joints
  • • Tender joints
  • • C-reactive protein (CRP).

Approval duration

12 months