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CaracCareFirst (Caremark)

External genital warts (EGW)

Preferred products

  • imiquimod 5 percent cream
  • fluorouracil cream
  • fluorouracil solution

Initial criteria

  • For Actinic Keratosis (AK): Authorization may be granted when ONE of the following is met:
  • • The request is for Carac, Tolak, OR Zyclara.
  • • The request is for Klisyri AND the patient experienced an inadequate treatment response, intolerance, OR has a contraindication to ANY of the following: imiquimod 5 percent cream, fluorouracil cream or solution.
  • For External Genital Warts (EGW): Authorization may be granted when the request is for Zyclara.

Reauthorization criteria

  • For Actinic Keratosis (AK): The patient has achieved or maintained a positive clinical response as evidenced by improvement (e.g., percentage of actinic keratosis lesions cleared, patient/prescriber satisfaction, etc.).
  • For External Genital Warts (EGW): The request is for Zyclara AND the patient has achieved or maintained a positive clinical response as evidenced by improvement (e.g., percentage of warts cleared).

Approval duration

Initial therapy: 4 months; Continuation: 12 months