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Enbrel (etanercept)CareFirst (Caremark)

Moderately to severely active rheumatoid arthritis (RA)

Initial criteria

  • Age ≥ 18 years
  • Member meets either of the following biomarker conditions: (a) tested for rheumatoid factor (RF) or anti-cyclic citrullinated peptide (anti-CCP) and result positive; OR (b) tested for all biomarkers RF, anti-CCP, and C-reactive protein (CRP) and/or erythrocyte sedimentation rate (ESR)
  • Member meets ONE of the following: (a) failed 3-month trial of methotrexate (MTX) monotherapy at ≥15 mg/week and had inadequate response to or intolerance/contraindication to hydroxychloroquine and/or sulfasalazine; OR (b) unable to tolerate MTX and had inadequate response to or intolerance/contraindication to leflunomide, hydroxychloroquine, or sulfasalazine; OR (c) has contraindications to MTX, leflunomide, hydroxychloroquine, and sulfasalazine
  • Member has moderate to high disease activity

Reauthorization criteria

  • Chart notes or medical record documentation supporting positive clinical response

Approval duration

12 months