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FerriproxCareFirst (Caremark)

Transfusional iron overload due to thalassemia syndromes

Initial criteria

  • Transfusional iron overload is due to thalassemia syndromes OR sickle cell disease or other anemias
  • Member does not have transfusional iron overload due to myelodysplastic syndrome or Diamond Blackfan anemia
  • Pretreatment serum ferritin level is consistently greater than 1000 mcg/L
  • Dose will not exceed 99 mg/kg per day

Reauthorization criteria

  • Member is experiencing benefit from therapy as evidenced by a decrease in serum ferritin levels as compared to pretreatment baseline
  • Serum ferritin level is not consistently below 500 mcg/L

Approval duration

12 months