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GilotrifCareFirst (Caremark)

Metastatic non-small cell lung cancer (NSCLC) with EGFR-sensitizing mutation-positive disease

Initial criteria

  • Diagnosis of recurrent, advanced or metastatic non-small cell lung cancer (NSCLC)
  • Disease is EGFR-sensitizing mutation-positive confirmed by an FDA-approved test
  • Used as a single agent or in combination with cetuximab OR
  • Diagnosis of metastatic squamous NSCLC progressing after platinum-based chemotherapy

Reauthorization criteria

  • No evidence of unacceptable toxicity or disease progression while on the current regimen OR
  • Disease is T790M negative and there is no evidence of unacceptable toxicity

Approval duration

12 months