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Iclusig (ponatinib)CareFirst (Caremark)

Philadelphia chromosome positive (Ph+) Acute Lymphoblastic Leukemia (ALL) / Lymphoblastic Lymphoma (LL)

Initial criteria

  • Ph+ ALL/LL confirmed by detection of Ph chromosome or BCR::ABL gene by cytogenetic and/or molecular testing

Reauthorization criteria

  • No evidence of unacceptable toxicity or disease progression while on current regimen AND
  • Ph+ ALL/LL confirmed by detection of Ph chromosome or BCR::ABL gene by cytogenetic and/or molecular testing OR
  • Member has received HSCT for ALL/LL

Approval duration

12 months