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Iwilfin (eflornithine)CareFirst (Caremark)

Reduce the risk of relapse in adult and pediatric patients with high-risk neuroblastoma (HRNB) who have demonstrated at least a partial response to prior multiagent, multimodality therapy including anti-GD2 immunotherapy

Initial criteria

  • Member has high-risk neuroblastoma (HRNB)
  • Member has demonstrated at least a partial response to prior multiagent, multimodality therapy including anti-GD2 immunotherapy (e.g., dinutuximab [Unituxin], naxitamab-gqgk [Danyelza])

Reauthorization criteria

  • Request is for continued treatment of the indication listed in the coverage criteria section
  • No evidence of unacceptable toxicity or disease progression while on the current regimen

Approval duration

12 months (up to 24 months total therapy)