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Kisqali Femara Co-PackCareFirst (Caremark)

HR-positive, HER2-negative recurrent or metastatic breast cancer

Initial criteria

  • For breast cancer, member has HR-positive, HER2-negative disease
  • For adjuvant treatment of early-stage breast cancer, member has HR-positive, HER2-negative disease at high risk of recurrence (defined as any lymph node involvement excluding microscopic nodal involvement, or no nodal involvement and tumor size greater than 5 cm, or tumor size 2 to 5 cm and Grade 2 with high genomic risk or Ki-67 ≥ 20% or Grade 3)
  • For endometrial carcinoma, member has recurrent or metastatic disease with ER-positive tumors
  • Documentation of HR and HER2 status for breast cancer or ER status for endometrial carcinoma is provided

Reauthorization criteria

  • For early-stage HR-positive, HER2-negative breast cancer, authorization may continue until completion of 3 years of treatment or until disease recurrence or unacceptable toxicity while on the current regimen
  • For recurrent or metastatic breast cancer or endometrial carcinoma, continue if there is no evidence of unacceptable toxicity or disease progression while on the current regimen

Approval duration

12 months