metyrosine — CareFirst (Caremark)
Pheochromocytoma/Paraganglioma
Initial criteria
- Member has experienced an inadequate treatment response, intolerance, or has a contraindication to an alpha-adrenergic antagonist (e.g., terazosin, doxazosin, prazosin, phenoxybenzamine)
 - AND one of the following:
 - Requested agent will be used for preoperative preparation for surgery
 - OR requested agent will be used for management when surgery is contraindicated
 - OR requested agent will be used for chronic treatment for malignant pheochromocytoma
 
Reauthorization criteria
- Member has improvement in symptoms (e.g., blood pressure, heart rate, headaches, sweating, anxiety)
 - AND no unacceptable toxicity while on the current regimen
 
Approval duration
12 months