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metyrosineCareFirst (Caremark)

Pheochromocytoma/Paraganglioma

Initial criteria

  • Member has experienced an inadequate treatment response, intolerance, or has a contraindication to an alpha-adrenergic antagonist (e.g., terazosin, doxazosin, prazosin, phenoxybenzamine)
  • AND one of the following:
  • Requested agent will be used for preoperative preparation for surgery
  • OR requested agent will be used for management when surgery is contraindicated
  • OR requested agent will be used for chronic treatment for malignant pheochromocytoma

Reauthorization criteria

  • Member has improvement in symptoms (e.g., blood pressure, heart rate, headaches, sweating, anxiety)
  • AND no unacceptable toxicity while on the current regimen

Approval duration

12 months