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NoxafilCareFirst (Caremark)

Oropharyngeal candidiasis (moderate to severe)

Preferred products

  • fluconazole
  • itraconazole oral solution

Initial criteria

  • For oropharyngeal candidiasis: the request is for Noxafil oral suspension (immediate-release)
  • For oropharyngeal candidiasis: patient has experienced an inadequate treatment response, intolerance, or has a contraindication to fluconazole AND itraconazole oral solution
  • For prevention of invasive Aspergillus and Candida infections: requested drug is being prescribed for a patient who is at high risk of developing these infections due to being severely immunocompromised
  • For treatment of invasive aspergillosis: requested drug is for Noxafil injection or Noxafil delayed-release tablets

Approval duration

Oropharyngeal candidiasis: 1 month; Prevention of invasive Aspergillus and Candida infections: 6 months; Treatment of invasive aspergillosis: 3 months