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Orenitram (treprostinil)CareFirst (Caremark)

Pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group 1)

Initial criteria

  • Member has PAH defined as WHO Group 1 class of pulmonary hypertension.
  • PAH was confirmed by either of the following criteria:
  • Pretreatment right heart catheterization with ALL of the following results:
  • Mean pulmonary arterial pressure (mPAP) > 20 mmHg
  • Pulmonary capillary wedge pressure (PCWP) ≤ 15 mmHg
  • Pulmonary vascular resistance (PVR) > 2 Wood units. For pediatric members, pulmonary vascular resistance index (PVRI) > 3 Wood units × m² is also acceptable.
  • For infants less than one year of age, PAH was confirmed by Doppler echocardiogram if right heart catheterization cannot be performed.
  • Medication must be prescribed by or in consultation with a pulmonologist or cardiologist.

Reauthorization criteria

  • Member is currently receiving the requested medication through a paid pharmacy or medical benefit.
  • Member is experiencing benefit from therapy as evidenced by disease stability or disease improvement.

Approval duration

12 months