Oxervate — CareFirst (Caremark)
neurotrophic keratitis
Initial criteria
- Authorization of 16 weeks (8 weeks total therapy per eye) may be granted for treatment of stage 2 and stage 3 neurotrophic keratitis when all of the following criteria are met:
 - The member must experience persistent epithelial defects (PED) or corneal ulceration of at least 2 weeks duration refractory to one or more conventional non-surgical treatments (e.g., preservative free artificial tears).
 - There is evidence of decreased corneal sensitivity (e.g., cotton swab method, Cochet-Bonnet contact aesthesiometer, CRCERT-Belmonte non-contact aesthesiometer) within the area of the PED or corneal ulcer and outside of the area of the defect in at least one corneal quadrant.
 - The member has not received a previous 8-week course of Oxervate in the affected eye.
 - This medication must be prescribed by or in consultation with an ophthalmologist or optometrist.
 
Approval duration
16 weeks (8 weeks total therapy per eye)