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Pemazyre (pemigatinib)CareFirst (Caremark)

Cholangiocarcinoma with FGFR2 fusion or rearrangement

Initial criteria

  • Member has progressive, unresectable, resected gross residual (R2) disease or metastatic cholangiocarcinoma
  • Disease has a fibroblast growth factor receptor 2 (FGFR2) fusion or rearrangement documented by an FDA-approved test
  • Pemazyre will be used as a single agent

Reauthorization criteria

  • No evidence of unacceptable toxicity or disease progression while on current regimen

Approval duration

12 months