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PromactaCareFirst (Caremark)

Severe aplastic anemia – insufficient response to immunosuppressive therapy

Initial criteria

  • Member has had an insufficient response to prior immunosuppressive therapy

Reauthorization criteria

  • Authorization of up to 16 weeks total if current platelet count <50×10^9/L and member has not received appropriately titrated therapy for ≥16 weeks
  • Authorization of 12 months total if current platelet count <50×10^9/L and member is transfusion-independent
  • Authorization of 12 months if current platelet count 50×10^9/L–200×10^9/L
  • Authorization of 12 months if current platelet count >200×10^9/L to ≤400×10^9/L and dosing will be adjusted to maintain an appropriate platelet count

Approval duration

initial 6 months; continuation up to 16 weeks or 12 months per criteria