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Qinlock (ripretinib)CareFirst (Caremark)

Gastrointestinal stromal tumor (GIST)

Initial criteria

  • Diagnosis of advanced, gross residual (R2 resection), unresectable, tumor rupture, recurrent, or metastatic GIST
  • Used as a single agent
  • Member has previously received treatment with 3 or more kinase inhibitors, including imatinib OR member has experienced disease progression on avapritinib and dasatinib OR member is intolerant to sunitinib as second-line therapy after imatinib

Reauthorization criteria

  • No evidence of unacceptable toxicity while on the current regimen

Approval duration

12 months