Saizen — CareFirst (Caremark)
Russell-Silver syndrome
Initial criteria
- Authorization of 12 months when ALL:
 - For members <2.5 years: pretreatment height >2 SD below mean and slow growth velocity
 - For members ≥2.5 years: pretreatment height >2 SD below mean and 1-year height velocity >1 SD below mean OR 1-year velocity >2 SD below mean
 - Epiphyses open
 
Reauthorization criteria
- Continuation authorization for 12 months if currently receiving GH therapy, epiphyses open, growth rate >2 cm/year unless clinically justified
 
Approval duration
12 months