Tobramycin sulfate injection — CareFirst (Caremark)

Initial criteria

• Aminoglycosides, including tobramycin sulfate, are not indicated in uncomplicated initial episodes of urinary tract infections unless the causative organisms are not susceptible to antibiotics having less potential toxicity
• Tobramycin may be considered in serious staphylococcal infections when penicillin or other potentially less toxic drugs are contraindicated and when bacterial susceptibility testing and clinical judgment indicate its use
• Bacterial cultures should be obtained prior to and during treatment to isolate and identify etiologic organisms and to test their susceptibility to tobramycin
• If susceptibility tests show that the causative organisms are resistant to tobramycin, other appropriate therapy should be instituted
• Tobramycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria