Skip to content
The Policy VaultThe Policy Vault

Tygacil (tigecycline)CareFirst (Caremark)

Complicated skin and skin structure infections caused by susceptible isolates of Escherichia coli, Enterococcus faecalis (vancomycin-susceptible isolates), Staphylococcus aureus (methicillin-susceptible and -resistant isolates), Streptococcus agalactiae, Streptococcus anginosus group (includes S. anginosus, S. intermedius, and S. constellatus), Streptococcus pyogenes, Enterobacter cloacae, Klebsiella pneumoniae, and Bacteroides fragilis

Initial criteria

  • Patient age ≥ 18 years
  • Indicated infection proven or strongly suspected to be caused by susceptible bacteria
  • Tygacil should not be used for diabetic foot infections
  • Tygacil should not be used for hospital-acquired or ventilator-associated pneumonia
  • Appropriate cultures obtained to isolate and identify organisms and determine susceptibility
  • Use of Tygacil should be limited to treatment of infections proven or strongly suspected to be due to susceptible bacteria