Vowst (fecal microbiota spores, live-brpk) — CareFirst (Caremark)
Prevention of recurrence of Clostridioides difficile infection (CDI)
Initial criteria
- Member age ≥ 18 years
- Member has had three or more episodes of CDI within the past 12 months (including the most recent episode)
- Member has a recent episode of recurrent CDI with all of the following:
- • At least 3 unformed stools per day for 2 consecutive days
- • Stool test confirming the presence of C. difficile toxin or toxigenic C. difficile
- • Adequate clinical response (e.g., resolution of symptoms) following standard of care antibiotic therapy (e.g., vancomycin, fidaxomicin)
Approval duration
30 days for a one-time treatment