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Vyalev (foscarbidopa/foslevodopa)CareFirst (Caremark)

Treatment of motor fluctuations in adults with advanced Parkinson’s disease

Initial criteria

  • Member has advanced Parkinson’s disease
  • Member is levodopa responsive with clearly defined “on” periods
  • Member has “off” periods of at least 2.5 hours per day despite optimization efforts
  • Member has had an inadequate response or intolerable adverse event with oral carbidopa/levodopa and one of the following anti-Parkinson agents: Dopamine agonist (e.g., pramipexole, ropinirole) OR Monoamine oxidase-B (MAO-B) inhibitor (e.g., selegiline, rasagiline) OR Catechol-O-methyltransferase (COMT) inhibitor (e.g., entacapone, tolcapone)

Reauthorization criteria

  • Member has demonstrated a positive clinical response with Vyalev for continued treatment of advanced Parkinson’s disease

Approval duration

Initial: 6 months; Continuation: 12 months