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WakixCareFirst (Caremark)

Excessive daytime sleepiness (EDS) with narcolepsy

Preferred products

  • armodafinil
  • modafinil
  • amphetamine
  • dextroamphetamine
  • methylphenidate

Initial criteria

  • The diagnosis of narcolepsy is confirmed by a sleep lab evaluation.
  • For EDS with narcolepsy: member is age 6 years to <18 years and has experienced inadequate treatment response or intolerance to at least one CNS stimulant (e.g., amphetamine, dextroamphetamine, methylphenidate) OR has a contraindication to at least one CNS stimulant.
  • For EDS with narcolepsy: member is age ≥18 years and has experienced inadequate treatment response or intolerance to armodafinil or modafinil OR has contraindications to both armodafinil and modafinil.
  • For cataplexy with narcolepsy: diagnosis of narcolepsy is confirmed by a sleep lab evaluation and the member experiences at least 3 cataplexy attacks per week.
  • Medication must be prescribed by or in consultation with a sleep specialist (e.g., neurologist experienced with sleep disorders, physician certified in sleep medicine).

Reauthorization criteria

  • For EDS with narcolepsy: the member has demonstrated beneficial response to treatment as defined by a decrease in symptoms of daytime sleepiness from baseline.
  • For cataplexy with narcolepsy: the member has demonstrated beneficial response to treatment as defined by a decrease in cataplexy episodes from baseline.

Approval duration

12 months