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Xalkori (crizotinib)CareFirst (Caremark)

Non-Small Cell Lung Cancer (NSCLC)

Initial criteria

  • Member has recurrent, advanced or metastatic ALK-rearrangement positive NSCLC and will be used as a single agent
  • OR Member has recurrent, advanced or metastatic ROS1-rearrangement positive NSCLC and will be used as a single agent
  • OR Member has recurrent, advanced or metastatic MET exon 14 skipping mutation-positive NSCLC and will be used as a single agent
  • OR Member has metastatic NSCLC with high-level MET amplification

Reauthorization criteria

  • Authorization may be renewed when there is no evidence of unacceptable toxicity while on the current regimen

Approval duration

12 months