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XtandiCareFirst (Caremark)

Castration-resistant prostate cancer (CRPC)

Initial criteria

  • For castration-resistant prostate cancer (CRPC): Member has had a bilateral orchiectomy OR will be using the requested medication in combination with a luteinizing hormone-releasing hormone (LHRH) agonist (e.g., goserelin, leuprolide) or antagonist (degarelix, relugolix).
  • For metastatic castration-sensitive prostate cancer (mCSPC): Member has had a bilateral orchiectomy OR will be using the requested medication in combination with a luteinizing hormone-releasing hormone (LHRH) agonist (e.g., goserelin, leuprolide) or antagonist (degarelix, relugolix).
  • For non-metastatic castration-sensitive prostate cancer (nmCSPC): Member has biochemical recurrence at high risk for metastasis.

Reauthorization criteria

  • Continuation of therapy may be granted when there is no evidence of unacceptable toxicity or disease progression while on the current regimen.

Approval duration

12 months