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The Policy VaultThe Policy Vault

ZytigaCareFirst (Caremark)

Prostate cancer

Initial criteria

  • Member has had a bilateral orchiectomy OR will be using the requested medication with a luteinizing hormone-releasing hormone (LHRH) agonist (e.g., goserelin, leuprolide) or antagonist (e.g., degarelix, relugolix)
  • AND one of the following: (a) disease is non-metastatic and node positive, high-risk, or very-high-risk; OR (b) disease is metastatic
  • For salivary gland tumor: authorization may be granted for recurrent, unresectable, or metastatic salivary gland tumor in combination with prednisone when the tumor is androgen receptor positive

Reauthorization criteria

  • No evidence of unacceptable toxicity or disease progression while on the current regimen

Approval duration

12 months