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Arcalyst (rilonacept subcutaneous injection)Cigna

Cryopyrin-Associated Periodic Syndromes (CAPS) including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), and/or neonatal onset multisystem inflammatory disease (NOMID) formerly known as chronic infantile neurological cutaneous and articular syndrome (CINCA)

Initial criteria

  • Patient is age ≥ 12 years; AND
  • The medication is prescribed by or in consultation with a rheumatologist, geneticist, allergist/immunologist, or dermatologist

Reauthorization criteria

  • Patient has been established on this medication for at least 6 months; AND
  • Patient meets at least ONE of the following: (a) When assessed by at least one objective measure, patient experienced a beneficial clinical response from baseline (prior to initiating the requested drug); OR (b) Compared with baseline, patient experienced an improvement in at least one symptom

Approval duration

initial 6 months; reauth 1 year