Ayvakit (avapritinib tablets) — Cigna
Gastrointestinal stromal tumor (GIST)
Initial criteria
- Patient age ≥ 18 years
- EITHER tumor is positive for platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation (includes PDGFRA D842V mutation) OR patient has tried ALL of the following: imatinib, one of sunitinib or Sprycel (dasatinib tablets), Stivarga (regorafenib tablets), and Qinlock (ripretinib tablets)
Approval duration
1 year