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Cotellic (cobimetinib tablets – Genentech/Roche)Cigna

Central Nervous System Cancer

Initial criteria

  • Patient age ≥ 18 years
  • Medication is being used for ONE of the following: Adjuvant treatment of pilocytic astrocytoma OR pleomorphic xanthoastrocytoma OR circumscribed ganglioglioma/neuroglioma/glioneuronal tumor OR Recurrent or progressive high-grade glioma OR circumscribed glioma OR glioblastoma OR Brain metastases due to melanoma
  • Patient has BRAF V600 mutation-positive disease
  • Medication is prescribed in combination with Zelboraf (vemurafenib tablets)

Approval duration

1 year