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Dibenzyline (phenoxybenzamine capsules)Cigna

Pheochromocytoma

Preferred products

  • generic phenoxybenzamine

Initial criteria

  • For Dibenzyline (phenoxybenzamine): Approve for 1 year if BOTH of the following are met (A and B):
  • A) If brand Dibenzyline is requested, patient meets BOTH of the following (i and ii):
  • i. Patient has tried generic phenoxybenzamine; AND
  • ii. Patient cannot continue to use generic phenoxybenzamine due to a formulation difference in the inactive ingredient(s) [e.g., difference in dyes, fillers, preservatives] between the brand and the bioequivalent generic product which, according to the prescriber, would result in a significant allergy or a serious adverse reaction [documentation required]; AND
  • B) The medication is prescribed by or in consultation with an endocrinologist or a physician who specializes in the management of pheochromocytoma.
  • For Demser (metyrosine): Approve for 1 year if ONE of the following (A or B) is met:
  • A) Initial Therapy: Approve for 1 year if ALL of the following (i, ii, and iii) are met:
  • i. Patient has tried a selective alpha blocker (e.g., doxazosin, terazosin, or prazosin); AND
  • ii. Patient has tried phenoxybenzamine (brand or generic); AND
  • iii. The medication is prescribed by, or in consultation with, an endocrinologist or a physician who specializes in the management of pheochromocytoma; OR
  • B) Patient is currently receiving metyrosine and it is prescribed by or in consultation with an endocrinologist or a physician who specializes in the management of pheochromocytoma.

Reauthorization criteria

  • Patient is currently receiving metyrosine and it is prescribed by or in consultation with an endocrinologist or a physician who specializes in the management of pheochromocytoma.

Approval duration

1 year