Dupixent — Cigna
Eosinophilic Esophagitis
Initial criteria
- Patient is age ≥ 1 year; AND
- Patient weighs ≥ 15 kg; AND
- Diagnosis confirmed by endoscopic biopsy showing ≥15 intraepithelial eosinophils per high-power field; AND
- Patient does not have a secondary cause of eosinophilic esophagitis; AND
- Patient has received at least 8 weeks of therapy with a proton pump inhibitor; AND
- Patient meets ONE of the following (a or b):
- a) Tried dietary modifications to manage eosinophilic esophagitis; OR
- b) Provider determined patient is not an appropriate candidate for dietary modifications; AND
- Medication prescribed by or in consultation with an allergist or gastroenterologist.
Reauthorization criteria
- Patient has already received at least 6 months of therapy with Dupixent; AND
- Patient has experienced a beneficial clinical response, defined by ONE of the following (a, b, or c):
- a) Reduced intraepithelial eosinophil count; OR
- b) Decreased dysphagia/pain upon swallowing; OR
- c) Reduced frequency or severity of food impaction.
Approval duration
initial 6 months; reauth 1 year