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DupixentCigna

Eosinophilic Esophagitis

Initial criteria

  • Patient is age ≥ 1 year; AND
  • Patient weighs ≥ 15 kg; AND
  • Diagnosis confirmed by endoscopic biopsy showing ≥15 intraepithelial eosinophils per high-power field; AND
  • Patient does not have a secondary cause of eosinophilic esophagitis; AND
  • Patient has received at least 8 weeks of therapy with a proton pump inhibitor; AND
  • Patient meets ONE of the following (a or b):
  • a) Tried dietary modifications to manage eosinophilic esophagitis; OR
  • b) Provider determined patient is not an appropriate candidate for dietary modifications; AND
  • Medication prescribed by or in consultation with an allergist or gastroenterologist.

Reauthorization criteria

  • Patient has already received at least 6 months of therapy with Dupixent; AND
  • Patient has experienced a beneficial clinical response, defined by ONE of the following (a, b, or c):
  • a) Reduced intraepithelial eosinophil count; OR
  • b) Decreased dysphagia/pain upon swallowing; OR
  • c) Reduced frequency or severity of food impaction.

Approval duration

initial 6 months; reauth 1 year