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DupixentCigna

Prurigo Nodularis

Initial criteria

  • Patient is age ≥ 18 years; AND
  • Has ≥ 20 identifiable nodular lesions on arms, legs, and/or trunk; AND
  • Pruritus duration ≥ 6 weeks; AND
  • Either prurigo nodularis is not medication-induced/secondary OR secondary cause has been identified and managed; AND
  • Patient has tried at least one high- or super-high-potency topical corticosteroid applied daily for ≥14 consecutive days with inadequate efficacy; AND
  • Medication is prescribed by or in consultation with an allergist, immunologist, or dermatologist.

Reauthorization criteria

  • Patient has already received at least 6 months of therapy with Dupixent; AND
  • Patient has experienced a beneficial clinical response, defined by ONE of the following (a, b, or c):
  • a) Reduced nodular lesion count; OR
  • b) Decreased pruritus; OR
  • c) Reduced nodular lesion size.

Approval duration

initial 6 months; reauth 1 year