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Increlex (mecasermin [rDNA origin] subcutaneous injection - Ipsen)Cigna

Growth Hormone Gene Deletion with neutralizing antibodies to growth hormone

Initial criteria

  • Patient is ≥ 2 years of age; AND
  • The epiphyses are open; AND
  • Patient has developed neutralizing antibodies to growth hormone; AND
  • Patient will not be receiving concurrent treatment with growth hormone; AND
  • Medication is prescribed by or in consultation with a pediatric endocrinologist

Reauthorization criteria

  • Patient’s height has increased by ≥ 2 cm/year in the most recent year; AND
  • The epiphyses are open; AND
  • Patient has developed neutralizing antibodies to growth hormone; AND
  • Patient will not be receiving concurrent treatment with growth hormone

Approval duration

1 year